Connect with us

Brazil

Post-doctoral Fellowship in Pharmacy Chemistry

A postdoctoral fellow is available at Laboratory of Molecular Research in Cardiology (LIMC) from Instituto Dante Pazzanese de Cardiologia (IDPC), associated to Laboratory of Molecular Biology Applied to Diagnosis (LABMAD) from School of Pharmaceutical Sciences (USP-Brazil). The subproject linked to this fellowship has as main aim to develop a workflow for analysis of DNA and RNA sequencing data obtained from patients with Familial Hypercholesterolemia (HF) using bioinformatics tools.

For the development of the project, the post-doctorate will be subsidized with a postdoctoral fellowship from the São Paulo Research Foundation-FAPESP, Thematic Project entitled ” Modernization of the research infrastructure of the Dante Pazzanese Institute of Cardiology for innovation in the prevention, diagnosis and treatment of cardiovascular diseases”, validity of 01/01/2019 to 12/31/2020, having as a requirement a full time with exclusive dedication. The fellowship is R$ 7.373,10/month with duration of 24 months. 15% of the fellowship’s annual value will be granted to cover expenses directly related to research activities.

The requirements and benefits are available at http://fapesp.br/en/5427 .

Qualities and experience required

A – Interested candidates must have completed their doctorate for less than 7 years;
B – The position requires previous experience in pharmacy chemistry, molecular modelling including, but not limited to docking, virtual screening, 3D-pharmacophore modelling and molecular dynamics simulation, as well as some experience on assay development, particularly involving experimental validation of the in silico suggestions and development of new drugs. Experience with in vitro assays, by the means of enzymatic kinetic testing and molecular optimization, is an asset. Experience must be attested by means of a master’s thesis, doctoral thesis or equivalent title, as well as by track record with publications. 

Documents required for registration until 11/10/2018

Check out  Post-doctoral Fellowship in Mathematics Education

A – Applicants should send the following documents (in pdf format) to Prof. Mario H. Hirata: [email protected]  or [email protected] ;
B – Updated Lattes curriculum;
C – Interest letter, explaining the reasons for your application to the position;
D – Two letters of recommendation issued by professionals in your area of expertise

More information about the fellowship is at: http://www.fapesp.br/oportunidades/2429/

Visit Scholarship Website

Brazil

Post-doctoral Fellowship in Parasitology

The opportunity is for the project belonging to the Institutional Research Development Plan (PDIP), whose objective will be the development of scientific and technological solutions that will provide rapid and timely responses to strengthen laboratory actions in health surveillance. Project title: “Pre-clinical study of new candidate drugs against leishmaniasis”, coordinated by Dr. Andre Gustavo Tempone.

The present proposal aims to identify an approved drug by means of the drug repositioning or synthetic active compound based in a natural prototype, which presents promising anti-Leishmania infantum activity. The investigator will initially perform in vitro phenotypic assays using the intracellular amastigote model of Leishmania infantum to determine the activity of the compounds to be tested. Studies will be carried out in different cell lines to evaluate the mammalian cytotoxicity. Cellular studies, based on flow cytometry techniques, spectrofluorimetry and transmission electron microscopy will be used to investigate the possible mechanisms of action of the most promising compounds. Finally, in vitro pharmacokinetic studies (ADME) such as solubility, membrane permeability and metabolization will be performed as initial parameters for the design of animal model efficacy studies.

Pre-requisites for the position: Doctoral degree in area related to the project based on Drug Discovery in visceral leishmaniasis or Chagas disease; project experience involving techniques of phenotypic assays (intracellular amastigotes and cytotoxicity), experience in studies of cellular action mechanism; experience in pharmacokinetic profile studies and in vivo efficacy studies. 

Candidates need to send an e-mail to the researcher Dr. Andre G. Tempone ([email protected] ), containing curriculum vitae, letters of presentation justifying the interest in the vacancy and letters of recommendation with contacts (name, institution, telephone and e-mail) of two researchers who can give information about the candidate.

The project will be funded by São Paulo Research Foundation – FAPESP (www.fapesp.br/en ). The vacancy is open to Brazilians and foreigners. The selected will receive FAPESP Post-Doctoral Fellowship (www.fapesp.br/en/postdoc ) in the amount of BRL7,373.10 per month and Technical Reserve. The Technical Reserve of PD Grant is equivalent to 15% of the annual value of the scholarship and is intended to meet unforeseen expenses directly related to the research activity.

Check out  Post-doctoral Fellowship in Mathematics Education

More information about the fellowship is at: fapesp.br/oportunidades/2415 .

Visit Scholarship Website

Continue Reading

Brazil

Post-doctoral Fellowship in Molecular Biology

The research group Bioproducts’ Production and Purification Lab (BioPPuL), located in the Department of Bioprocesses and Biotechnology of the FCFAr of UNESP, offers a postdoctoral fellowship to develop the recombinant microorganism for the production of L-asparaginase (ASNase) and studies of its production process by submerged cultivation.

About the project

Getting older is the biggest risk factor for most fatal diseases, including cancer, heart disease and Alzheimer’s. The advances in nanomedicine comprise the development of nanoparticles either for drug delivering or as platforms for biomolecules purification. Simultaneously, continuous progresses have been made for the development of recombinant therapeutic enzymes, namely L-asparaginase (LA), which presents antineoplastic properties for thetreatment of leukaemia’s, in particular for Acute Lymphoblastic Leukemia (ALL). Currently, the LA available in medical applications is produced from bacteria. However, this type of LA may activate the immunological system causing human hypersensitivity reactions. Therefore, the search for novel microorganisms able to produce LA with no side effects has been the main focus of many researches.

Considering the great demand for the development of new technologies for the purification of therapeutic enzymes, still limited by their high cost, this project aims to produce recombinant LA by bacteria fermentation and to developa cost-effective and sustainable platform for the biopharmaceutical purification (downstream processing) from the fermentation broth using nanomaterials. The main goal is to obtain recoveries of LA above 90% and purity levels over 95%, with a cost reduction around 20%. A critical evaluation of the best strategies and conditions for the integrationprocesses and scale-up will be explored.

Check out  Post-doctoral Fellowship in Electro-Oxidation of Ethanol, Glycerol and Other Organic Molecules

The involved research teams (CICECO, FEUP and UNESP) have shown to be successful in providing pioneering scientific results on the production of enzymes and on the development of separation and purification techniques for biopharmaceuticals. The UNESP team from Brazil will optimise noveltechniques of heterologous enzyme production by bacterial fermentation, which is generally regarded as safe (GRAS) and easy to manipulate, in order to achieve higher enzyme yields. The Portuguese teams (CICECO and FEUP) will be responsible for the preparation of functionalisation of silica and carbon nanomaterials, which will be used as an efficient and fast strategy for LA purification from the fermentation medium. NanoPurAsp aims to meet the approval of biopharmaceuticals by regulatory authorities which require effective and high quality biopharmaceuticals, i.e., no side-effects, high purity and biological activity. These can only be attained through in-depth knowledge of the products and of their manufacturing processes. The advanced research here produced will certainly allow the success of therapeutic enzymes production and its easy scalability up to industrial levels at a lower cost. The integrated process developed will have a great impact in economy with a long-term impact in human healthcare. This project aspires the optimization of resources and materials which will contribute to a greener and sustainable growth, which in turn will be a source of economic valorisation for the future industrial manufacturing.

Regarding the candidate:

– Candidate must have PhD in Biotechnology or related disciplines;
– Have completed the PhD no longer than 2 years prior to application;
– Proven international experience in groups outside the institution of origin of the doctorate;
– Excellent early achievement track record (scientific publications and /or patent deposits).

Check out  RecSports staff positions (Summer)

Specific Qualifications:

– Experience with Molecular Biology techniques;
– Experience with cultivation and handling of microorganisms, mainly bacteria;
– Experience with submerged cultivation;
– Desirable knowledge of bioreactors.

Applications should send the documents listed below to Prof. Dr. Valéria de Carvalho Santos Ebinuma (Principal investigator) by email: [email protected] . Deadline: 12/01/2018.

1) CV lattes updated (Brazilian) or CV with academic experience (foreigners);
2) Cover letter explaining what are the applicant’s motivations to undertake the project, as well as her/his qualification;
3) References (2 contacts).

This opportunity is open to candidates of any nationalities. The selected candidate will receive a FAPESP’s Post-Doctoral fellowship in the amount of R$ 7,373.10 monthly and a research contingency fund, equivalent to 15% of the annual value of the fellowship which should be spent in items directly related to the research activity.  

More information about the fellowship is at: fapesp.br/oportunidades/2480 .

Visit Scholarship Website

Continue Reading

Brazil

Master’s Fellowship in Bioinformatics

The Laboratory of Molecular Biology from the Blood Center of Ribeirão Preto, Brazil, offers one position for a master degree student with a basic knowledge of bioinformatics. The student will be responsible for the optimization and the implementation of a pipeline for the analysis of the viral metagenome (filtering sequences, alignments, taxonomic designation, de novo genome assembly) obtained from plasma and hemoderivatives. To start the working of this project, the student will receive training by international researchers from the Pasteur Institute. The student will be supervised by Dr. Svetoslav Slavov (https://bv.fapesp.br/en/pesquisador/83362/svetoslav-nanev-slavov/ ). The scholarship and the technical reserve values are pre-establshed by the Sao Paulo Research Foundation — FAPESP.

The blood center of Ribeirão Preto is a leading research institution which is funded by FAPESP, Brazil’s National Council for Scientific and Technological Development — CNPq and the Brazilian Innovation Agency — FINEP, and has an excellent infrastructure. More than 100 researchers work in the Blood Center of Ribeirão Preto in different research areas. One of the main lines of investigations includes the infectious diseases which can be transmitted via blood transfusion and the measures which can be undertaken to prevent such a process. 

Basic requirements: Linux; Program languages perl, python, and/or R; data banks; Analysis of next generation sequencing raw data is a plus. 

Those who are interested in this position, please send your CV, motivation letter and one recomendation letter of the Secretariat of Research of the Blood Center of Ribeirão Preto until 20/12/2018 ([email protected] r) mentioning the running head Mestrado_FAPESP_Slav and with a copy to [email protected]

More information about the fellowship is at: fapesp.br/oportunidades/2475 .

Check out  Religious Life and Campus Ministry - Student Worker 2018-2019

Visit Scholarship Website

Continue Reading

More Scholarships

Postgraduate Scholarships2 years ago

Classroom Assistant II (Part Time-4 Positions)

131 Position Details Position Information Recruitment/Posting Title Classroom Assistant II (Part Time-4 Positions) Posting Number 18TM0693 Department Ctr-Strategic Urban Ldrshp-Cmd...

Postgraduate Scholarships2 years ago

Osteoporosis Prevention & Treatment Ctr Student Worker

96 Working Title Osteoporosis Prevention & Treatment Ctr Student Worker Anticipated Starting Academic Term Fall Job Type Student Job Category...

Postgraduate Scholarships2 years ago

Student Software Developer (FALL)

62 Student Software Developer (FALL) – Job Number:  183298 Organization : CIMMSJob Location : United States-Oklahoma-NormanSchedule : Part-timeWork Schedule: Flexible, 10-20 hours per weekSalary Range: $10.00Benefits Provided: No Required Attachments: Resume,...

Postgraduate Scholarships2 years ago

Cross-Disciplinary Faculty Position: Illustration/Drawing/Digital Media

53 Posting Details Indiana University is an equal employment and affirmative action employer and a provider of ADA services. All...

Postgraduate Scholarships2 years ago

Cross-Disciplinary Faculty Position: Ceramics/Digital Ceramics

36 Posting Details Indiana University is an equal employment and affirmative action employer and a provider of ADA services. All...

Postgraduate Scholarships2 years ago

JMU X-Labs Student Intern – IE

26 Position Details Position Information Working Title JMU X-Labs Student Intern – IE Posting Number J1255 Position Type Institutional Employment...

Postgraduate Scholarships2 years ago

General Archives Student Assistant

34 Posting Details Posting Details Job Title General Archives Student Assistant Requisition Number DU04595 Department Name 88000:LIBRARY ADMINISTRATION Work Location...

Postgraduate Scholarships2 years ago

Oral History Center Indexing Student Assistant

27 Posting Details Posting Details Job Title Oral History Center Indexing Student Assistant Requisition Number DU03576 Department Name 88000:LIBRARY ADMINISTRATION...

New Zealand2 years ago

Dullabh Education Award

32 About the scholarship Application status: Not currently open for applicationsApplicable study: Year 3 of a BEd(Tchg) Primary, GradDipTchg(Sec) or...

Postgraduate Scholarships2 years ago

KMOS-TV Development Student Worker – Spring 2019

21 Position Information Position Information Position Title KMOS-TV Development Student Worker – Spring 2019 Working Title KMOS-TV Development Student Worker...

Follow on Instagram

Hey there!

Forgot password?

Forgot your password?

Enter your account data and we will send you a link to reset your password.

Your password reset link appears to be invalid or expired.

Close
of

    Processing files…