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The University of Saskatchewan values diversity, and Aboriginal engagement is a strategic priority.

Department: Biochemistry

FTE: 1

Status: Permanent

Shift:

Requisition: req1972

Open Date: 3/21/2018

Closing Date: 5/16/2018

Description: There is 1 opening for this posting. Located in Saskatoon.

M.Sc. position: A graduate student position is available immediately in the lab of Dr. Yuliang Wu at the Department of Biochemistry, College of Medicine, University of Saskatchewan. The lab is a part of “Cancer Cluster”, which houses 8 PIs and more than 40 researchers who have common interests in cancers. Dr. Wu’s group is particularly interested in cancers caused by DNA repair deficiency. Using molecular, biochemical, and cell biology approaches, this position will study the human single strand DNA binding protein (hSSB1/2) in transcriptional regulation under cellular genotoxic stress (Ref: Biochim Biophys Acta. 2016; 1860 (2):371-83 and Biochem J. 2018; 475 (1):45-60).

Conditions: $20,000/year; Start date: May 1st 2018 or September 1st 2018.

Qualifications: MSc applicants should have a bachelor’s degree from a recognized institute. The applicant should possess techniques in some of the following: molecular work (DNA and RNA), protein expression and purification, protein biochemical assays, tissue culture, and cell biology.  English language proficiency is required for admission according to College of Graduate Studies and Research: https://grad.usask.ca/admissions/admission-requirements.php#Englishlanguageproficiencyrequirements

How to Apply: Please send: 1) cover letter briefly describing your research interest and career goals, 2) your CV, and 3) a list of three references, by email to: [email protected]

The University of Saskatchewan is strongly committed to a diverse and inclusive workplace that empowers all employees to reach their full potential. All members of the university community share a responsibility for developing and maintaining an environment in which differences are valued and inclusiveness is practiced. The university welcomes applications from those who will contribute to the diversity of our community. All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

​

The University of Saskatchewan values diversity, and Aboriginal engagement is a strategic priority.

Department: Biochemistry

FTE: 1

Status: Permanent

Shift:

Requisition: req1972

Open Date: 3/21/2018

Closing Date: 5/16/2018

Description: There is 1 opening for this posting. Located in Saskatoon.

M.Sc. position: A graduate student position is available immediately in the lab of Dr. Yuliang Wu at the Department of Biochemistry, College of Medicine, University of Saskatchewan. The lab is a part of “Cancer Cluster”, which houses 8 PIs and more than 40 researchers who have common interests in cancers. Dr. Wu’s group is particularly interested in cancers caused by DNA repair deficiency. Using molecular, biochemical, and cell biology approaches, this position will study the human single strand DNA binding protein (hSSB1/2) in transcriptional regulation under cellular genotoxic stress (Ref: Biochim Biophys Acta. 2016; 1860 (2):371-83 and Biochem J. 2018; 475 (1):45-60).

Conditions: $20,000/year; Start date: May 1st 2018 or September 1st 2018.

Qualifications: MSc applicants should have a bachelor’s degree from a recognized institute. The applicant should possess techniques in some of the following: molecular work (DNA and RNA), protein expression and purification, protein biochemical assays, tissue culture, and cell biology.  English language proficiency is required for admission according to College of Graduate Studies and Research: https://grad.usask.ca/admissions/admission-requirements.php#Englishlanguageproficiencyrequirements

How to Apply: Please send: 1) cover letter briefly describing your research interest and career goals, 2) your CV, and 3) a list of three references, by email to: [email protected]

The University of Saskatchewan is strongly committed to a diverse and inclusive workplace that empowers all employees to reach their full potential. All members of the university community share a responsibility for developing and maintaining an environment in which differences are valued and inclusiveness is practiced. The university welcomes applications from those who will contribute to the diversity of our community. All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Description: There is 1 opening for this posting. Located in Saskatoon.

Opportunity to join a new and growing translational laboratory with a focus on multiple sclerosis.

The laboratory of Dr. Michael Levin in the Department of Anatomy and Cell Biology at the University of Saskatchewan has a position currently available for a Master’s student to study the role of abnormalities in the immune and nervous systems and how these abnormalities contribute to the pathogenesis of Multiple Sclerosis (MS).  The laboratory is located in Saskatoon City Hospital, as part of the Cameco MS Neuroscience Research Center.  For more information about the lab and Dr. Levin, please visit http://research-groups.usask.ca/skms-office/ .

The long-term goal of research in the Levin Lab is to better understand the cause of neurodegeneration, a salient feature and cause of permanent disability in progressive multiple sclerosis (MS) patients. For more than 20 years, we have studied the function of the RNA binding protein heterogeneous nuclear ribonuclear protein A1 (hnRNP A1 -‘A1’), with a focus on ‘M9’. M9 is A1’s nucleocytoplasmic transport domain and is required for transport of A1 between the nucleus and cytoplasm. Our lab has discovered that MS patients make antibodies to M9 and the brains and lymphocytes of MS patients contain somatic DNA mutations within M9. Using a number of molecular, in vitro and in vivo techniques, our data indicate that DNA mutations within M9 and autoimmunity to M9 result in A1 dysfunction and subsequent neuronal and axonal degeneration. Using this model, we examine potential mechanisms of neurodegeneration in MS resulting from A1 dysfunction.

The applicant should have a Bachelor’s degree in molecular cellular biology, biochemistry, neurology, neuroscience or a related field.  Familiarity in research using one or more of the following will be considered an asset; mouse models, imaging techniques (immunocytochemistry and immunohistochemistry), protein analyses, molecular biology techniques (PCR, cloning, etc.) and human tissue analyses.  Knowledge of data analysis and interpretation using statistical software is required.

The individual should be independent, self-motivated and should be able to perform tasks with modest supervision after receiving appropriate training. Applicants must have the ability to adhere to tight deadlines, be detail oriented, possess organizational skills, and keep meticulous records. As the laboratory is a shared space, strong interpersonal skills are necessary.  Successful applicants will be encouraged to apply for external funding opportunities.

Applicants should send the following documents to the Office of the Saskatchewan MS Clinical Research Chair via email to [email protected] :

• Current CV with list of laboratory experience
• Names and detailed contact information of three referees, one of whom should be your undergraduate research supervisor
• Statement of interest

Applicants are required to apply and be admitted to the Anatomy and Cell Biology graduate program, at the University of Saskatchewan in order to fill the position. Candidates whose first language is not English may be required to provide a certificate of English proficiency.  The English language requirements for a foreign candidate can be found at the CGPS website (www.usask.ca/cgps/ ).

This position is in scope of Grad Students – PSAC.

The University of Saskatchewan is strongly committed to a diverse and inclusive workplace that empowers all employees to reach their full potential. All members of the university community share a responsibility for developing and maintaining an environment in which differences are valued and inclusiveness is practiced. The university welcomes applications from those who will contribute to the diversity of our community. All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.